About 15 years ago, taking a daily Centrum led to a persistent state of elevated AST and ALT liver enzymes indicative of liver damage over a period of about 3 years. My doctor recommended I stop taking the vitamins and I have not had elevated liver enzymes even once in the last 15 years. Now I just take vitamin d (tested as deficient) and omega 3 fish oil for heart.
And then more recently there is evidence that taking vitamin supplements leads you to take risks with your health: http://www.theguardian.com/commentisfree/2011/aug/26/bad-sci...