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Fat


No deeper groves at 8?


That's because the XPS were built to run ubuntu. You can even buy one with it pre-installed.


I have Thinkpad which is supposedly built to run ubuntu as well and even certified for RHEL and Ubuntu. It doesn't work so good, though. It works, but there are rough edges around sleeping, external displays, power management.

I feel that it has nothing to do with manufacturer, though, just not good enough Linux support for laptops.


> It works, but there are rough edges around sleeping, external displays, power management.

Windows has these rough edges, too, though. It's actually pretty shocking that here in 2024, PC manufacturers and OS vendors are still struggling with basics like sleep/wakeup. Last job I had with Windows laptops, everyone would walk around the office from meeting to meeting with their laptops propped open because nobody could be sure that their OS would actually wake up when they opened the lid. And when you closed it and went home for the day, would standby actually work or would it be on fire and out of battery the next morning? Somehow, only Apple has seemed to be able to solve this Herculean problem.


> Somehow, only Apple has seemed to be able to solve this Herculean problem.

Bit of a stab in the dark here but I would assume ARM has at least something to do with this? Tablets, phones, etc. get standby a lot better than x86 systems seem to. My pre-M1 Macbook Pro does not handle standby well but my partner's M2 Macbook Air lasts for forever and handles sleep etc. well. The lower power consumption in "standby mode" on ARM seems like at least part of the picture for why Apple gets this so much better. I bet it's part of why Windows is trying to release their ARM variant and have been working on it for 10+ years


This used to work, but Windows/Intel have this new thing called Modern Standby that just doesn't do what anyone wants. It's on purpose. It's very frustrating.


> My pre-M1 Macbook Pro does not handle standby well but my partner's M2 Macbook Air lasts for forever and handles sleep etc. well.

Intel mac on sonoma?


I think so. My company's new refresh policy is "buy your own recycled corp device from us and we'll install all of our tracking software on it so you can use it as a corp device" (the _worst_ kind of BYOD imaginable). So, I'm probably using the initially "free" Intel Macbook until it dies, I do, or my job does.


If you have an issue with windows, it’s abnormal - while with linux is pretty expected on several fronts


> I feel that it has nothing to do with manufacturer, though, just not good enough Linux support for laptops.

On the contrary, it's down to the model. As I type this on a fully-functional Thinkpad, I can assure you Linux is fine on laptops.


Ubuntu 20.04 was preinstalled on my machine. But I reinstalled when I moved to a larger SDD. I think I still used the OEM install image too.


I can't help but wonder if Dell tweaked the firmware. I know that I, and everyone I've seen discuss it, haven't been able to get a vanilla XPS (non-Developer edition, sold with Windows) with a typical off-the-shelf distro, including Ubuntu, to work 100%.


I've had a Dell XPS 13 9343 (2017 model, non-Developer edition) running Fedora for years without problems. I suppose you might consider it cheating because I replaced the original Broadcom WiFi card with an Intel WiFi card, as that driver was a bit flaky in the early days (whereas the Intel driver has kernel support).

Other than the pitiful 4 hour battery life, the laptop still runs fine, and mostly does what I need it to do for a permanently-docked daily driver.


Hey there! I no longer use my 9343, but I remember I was not able to run Fedora without breaking the sound support for it (Ubuntu had some kernel option set on startup that put the sound card to some legacy mode, instead of the I2C that Windows used). And I never managed to setup palm rejection, it was a constant pain whenever I had to use the (otherwise excellent) trackpad.

(The external "carbon-like" skin texture just disintegrated on it after a few years, and the hinges got loose, but otherwise it is tip-top, still functional!)


If memory serves, the audio issue you're describing was fixed by a BIOS update:

https://wiki.archlinux.org/title/Dell_XPS_13_(9343)


That seems likely. I know that firmware is one of the big differences between System76 laptops and the version that Clevo subsequently offers with Windows. I think the chips can vary sometimes too.

Just from an ACPI perspective, I'd expect the Linux variant to (at a minimum) be built with the Intel compiler and the Windows one with Microsoft's. It is likely that there are far more differences, though.


The biggest problem with System76 laptops: their screens.

$1400 for a laptop with 1920x1080 at 60hz in 2024 is a joke. $200 more gets you a 3024x1964 @ 120hz, with an M3 processor and the ability to get warranty service walk-in anywhere around the world.


I agree that a better screen would be great, and walk-in service anywhere in the world would be fantastic.

But I want a Linux laptop, not Windows or OSX. I also want a computer that obeys me, not some megacorp (not unrelated to the previous point.) I also want to not fight it all the time.


I bought Dell 3410 once which was shipped with Ubuntu. I closely inspected that Ubuntu, compared it with vanilla Ubuntu install. All I've found are branding packages (desktop pictures, etc) and one package which blacklisted some module. No secret drivers, no secret kernels.

Can't comment about XPS, but I feel that it'll be the same.


Dell does the work to upstream the hardware support into the kernel. It's pretty rad. I miss my old XPS 13!


Sorry, I should have specified Developer Edition in my first post.


I ordered one with Ubuntu pre installed and it worked well, however there was an annoying issue where the mouse would freeze for a few seconds every couple minutes. I eventually swapped it with Garuda Linux and got a much faster UX, but suspend/sleep doesn't fully work. Doesn't bother me.


Anybody know why MRNA cancer vaccines didn't work out?

seems like it's almost the same methodology in making the immune system target specific proteins.


As somebody who unfortunately has a Stage IV diagnosis I have been researching mRNA and there have been promising results such as the MSK pancreatic study below, but still much to be ironed out — they had half the participants get a response but the other half nothing, even though each treatment was individually targeted and customized. They are doing a larger study now to try to see what other factors may be at play.

https://www.mskcc.org/news/can-mrna-vaccines-fight-pancreati...



mRNA vaccines need a target, and if there is a target, there are several approaches that already do this (anti-body drug conjugates), and sometimes work, sometimes doesn't.

I don't think anybody thinks it "didn't work out". It's still actively ongoing:

https://www.mdanderson.org/newsroom/md-anderson-curevac-ente...

https://investors.modernatx.com/news/news-details/2023/Moder...

(from 2021):

https://link.springer.com/article/10.1186/s12943-021-01348-0...

https://link.springer.com/article/10.1186/s12943-021-01348-0


Looks like doctors were able to treat brain cancer with a mRNA derived vaccine:

https://ufhealth.org/news/2024/uf-developed-mrna-vaccine-tri...


They do work, mainly for keeping a remissed cancer at bay.


They might but if I recall MRNA stuff is pretty new - and getting the clinical trials through the entire process and approval takes quite a long time.


The internet is weirdly quiet about this achievement


Yet one flap is going to be eternal in human memory


One flap we know of, it is quite possible its counterpart suffered the same fate. No matter, the ship remained manoeuvrable and performed the landing flip even with half a flap - or half of two flaps - missing. That is valuable data which shows the thing can survive such damage without losing control. Now they'll need to find some way to better seal those hinge areas from the 20 minute plasma torch it is subjected to during re-entry.


Aptly dubbed Flap Norris.


depends on your bubble.

my X is full of leaking flaps.


IIRC The original chips act had a provision that companies would have to train and hire X% of non-white/non-asian engineers.


Yeah.. Reddit shouldn't be relying on community moderators for larger subreddits.

They need paid people.


Then you have to find a way to store it.


Huh, if your electricity prices are low enough, it can quite worth it


It's not just bloat. It's also shitty devs that create more work for everybody else.


That's not how they decide who gets laid off.


It probably is sorry.


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