Computational biologist with a focus on predicting individual human health at a startup, but I have ended up managing software engineers. (Scientist explore and engineers make the science work in production.)

This explains the Scotch-Irish settling in Appalachia. It felt like home, but without the overbearing Brits nearby.

A lot also settled in the farmlands of Western Kentucky and brought sheep farming along with them, which is how it emerged as a very intense (mutton, pork, chicken, beef) bbq region.

Wait, where is BBQ mutton a thing?? I need a specific location for Waze, stat!

Owensboro has the best Old Hickory is the place you want, but there's also like a week of bbq festival every year with dozens and dozens of cooking teams. You'll find pockets of bbq in Madisonville, Lexington, Louisville, etc.

The mutton and chicken and pork is long cooked, low and slow, over hickory wood, and the baste and sauce has a lot of vinegar in it that breaks down the tough meat and makes it super tender. It's not spicy like the US west or southwest, and doesn't have all the sugar that Kansas City bbq does.

It is very, very good.

Also, burgoo soup!

Pretty much the whole of the Middle East, and consequently most of Glasgow following the various diasporas.

There used to be a place on Allison Street that did a kind of mutton liver and spinach stew with fenugreek and green chillis that I am currently right at this moment prepared to drive a 12-hour round trip to buy.

surely you mean overbearing English, old man?

No, we just found Nicola sturgeon’s hacker news account

Ya, the Scotch-Irish were the Brits doing the overbearing in Ireland.

Let’s also not forget that the Irish lords that the Anglo-Irish supplanted were themselves the descendants of Normans.

This is incorrect. It was the Britons that were ruled by saxons and then normans, not the Irish (until the invasion we’re talking about obviously).

No, they weren't, not in a meaningful way.

Appalachian Fae, mysterious lights, all the stories. Love it.

On the island of Ireland those people _are_ the overbearing Brits.

The English were in there centuries before them.

Scotland and Ireland were exchanging population for millennia because they are physically close. As soon as England got involved, trouble began.

The Readme for a UI library benefits enormously from screenshots, even terminal based UIs.

I second that, even better would be if every type chart would be a folder, with a readme containing a screenshot and the code example. That would be top notch.

PS: looks great on the surface!

Next updates will include better docs and many screenshots/examples, thanks!

If you don’t already have a preferred workflow for autogenerating these, you might be interested in vhs https://github.com/charmbracelet/vhs

I am not affiliated, I just think it’s a neat tool

Screenshots added for all widgets :) Flex layouts were added too!

The mind-body link is too important to get the causality wrong and The Body Keeps Score is an ideology where the causality only goes one way.

I have a cousin that had frequent, overwhelming anxiety attacks. She started eating breakfast consistently and the anxiety disappeared at the same time. Anxiety is strongly linked to gut activity, so the temporal correlation is a smoking gun, even if not dispositive.

For her, "understanding past trauma" was irrelevant to the solution.

> The Body Keeps [the] Score is an ideology where the causality only goes one way.

No it isn't. You might have interpreted it that way, but there's no such assertion. Quite the opposite in fact: the book details therapies like yoga, EMDR, neurofeedback, and somatic experiencing; each demonstrating body to mind causality.

I'm glad to hear how well this worked for your cousin! I don't eat breakfast often enough.

I specifically wanted to touch on the cycle of trauma & ADHD that's discussed in the article.

> That is, the ADHD leads to very negative experiences. Having had negative experiences (trauma) doesn’t lead to ADHD.

I think integrating traumatic experiences can have a lot of benefits to people, especially in the absence of easy fixes - as far as I know there's not really a smoking gun for ADHD, or borderline, etc. I'd argue the causality matters a bit less here. I say this even though I genuinely hated the fatalistic nature of the Body Keeps the Score, but I think Everett is a bit too quick to discard that the mind is relevant at all. I'd love to be proven wrong.

At least for myself, I've noticed increased well-being / reduced trauma responses when I avoid relationships that cause me a lot of stress, get enough sleep, and exercise regularly. But my baseline disposition is still there, and it's hard to untangle whether or not that's from trauma or from my body.

Everett argues that it's probably just my body (low T / high inflammation / too sensitive?) and I don't think that's very actionable. I'd argue that mind-body link goes in both directions, but that's purely anecdotal.

I also really liked softwaredoug's take on Adverse Childhood Experiences in the thread above.

This is really interesting on the ADHD side. For me, I’m pretty sure the traumatic experiences did lead to the ADHD. My mom kept all of my report cards and you can see exactly where it started. I wasn’t diagnosed until I was 36 or 37. I made it through undergrad (barely) and grad school (kicked ass in the challenging courses, took 6 years to finish an MSc thesis). After my diagnosis, I can retrospectively see a lot of ways my life could have been different if I’d known earlier but I have essentially no trauma caused by the ADHD traits other than a few failed relationships in my 20s.

Billions of cell derived from Henrietta Lacks agree with you.

I think you are getting at the need for tiered layers of abstraction and constraint. Simultaneously considering all possible ways to solve a problem doesn't work for humans or the LLMs derived from our use of language. The repeated use of Domain Specific Languages (DSL) in the context of a general purpose programming language gets at this same need to constrain solution spaces within a reasonable boundary.

Once we have quantum LLMs, the need for intermediate abstraction layers might change, but that's very [insert magic here].

Available data makes causality hard to get right. This paper is trying to get around known constraints with observational data (e.g., some people stop drinking when they start having noticeable problems). Mendelian randomization tries to infer how much a person drinks from their genetic variants. However, the genetic tendency to drink might be associated with the same variants related to dementia. The summary doesn't make it clear if this was addressed.

I didn't see a public source repository for keet, just compiled releases. Why would you trust closed source for a privacy app?

I’ve talked to their devs/met them in person and trust them, most of their stack is public/all the primitives they use are available and well documented (see https://github.com/holepunchto and https://docs.pears.com/), I’ve used that stack and verified it does what is advertised, and I believe they’re planning a full open source release of the parts that aren’t already public.

How does this avoid carrier grade NAT if everyone is on a cellphone?

IPv6? Every device from one of my networks has a different IP.

The language around emotion often obscures the underlying reality that needs to be addressed. Emotions are the physiological manifestations of expectations and desires. (Emotion is etymologically related to motive.)

The person your responding to clearly has a desire to do productive work with minimal roadblocks. In one person the roadblock to that desire/expectation might manifest physiologically as depression, in another person as anger, and in another as detachment. Getting rid of the roadblock is what needs to happen regardless of how the emotion manifests.

This does not mean that emotions are not addressed, but that they are addressed primarily as signifiers of a mismatch between the world and one's underlying desires/expectations, not the thing itself.

Sometimes, the desire/expectation of an individual is counter to the good of the overall system and group of people. In this case, a good manager might start by explaining the larger situation so that an individual can update their desires and expectations through the additional knowledge. Then new thinking/perception shifts the physiological experience of those desires (i.e., emotions).

In other cases, the gap between desires/expectations and reality is too big to bridge, which means emotions cannot be resolved in the current context.

Im curious, mostly for the sake of conversation, what emotional resolution looks like for you?