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It’s fairly common to use two hash functions and then compute the remaining n hashes as hn(x) = h1(x) + n * h2(x).

Paper: https://link.springer.com/chapter/10.1007/11841036_42


Feel obliged to point out this is misleading / not especially relevant: GDP is the value of the annual output of a country, while market capitalization is the (discounted) value of all future cash flows of a company. LVMH is ~0.5T market cap French company, but it’s nowhere near 1/6th of French economic output.

This is a lot like the recent “Novo Nordisk’s market cap is greater than the GDP of Denmark!” comparisons — true, but they’re not like numbers (and indeed, much of Novo Nordisk’s revenue is captured in Danish GDP).


Here's another comparison:

  # of Amazon employees:          1.7M

  # of working people in France:  30M
https://en.wikipedia.org/wiki/Amazon_(company)

https://tradingeconomics.com/france/employment-rate


I was looking at this a while back and it was difficult/tedious at the time (and I think also not supported on Amazon EKS).

Has it gotten better? Any resources you recommend? Cursory Google searches on this have so much outdated info it can be hard to quickly wade back in.


Futons are neither good couches nor good beds.


Which is not generally true if you have good (i.e. more expensive) futons.


And likewise if you throw a dedicated turn lane and some sidewalks at these roads they do a pretty ok job.


Absolutely not. If you're ever in Calgary, take a walk along Macleod trail near the Chinook centre. The sidewalks are filled with face-height street signage in the walkway, the sidewalks randomly venture between vehicle lanes, they'll sometimes just end, there are pedestrian road crossings without markings or signage, etc. It's one of the most unpleasant built environments I've ever encountered, up there with polluted Soviet mining cities.


I'm sure someone somewhere has managed to do it wrong but where I live it's done decently well and there's a fair number of main roads that meet the description I gave and are fine as a pedestrian, not perfect but fine.


Unprotected lefts have been widely recognized as one of the tasks that are especially difficult for autonomous driving to handle--which, of course, means that they can be relatively tricky for people too. And, yes, well-defined places to walk and cross streets help pedestrians--at least if they use those defined places which they often don't in cities.


What? Futons are not at all couches and great beds (for some people anyway, but I like’em). Do americans mean something weird by futons?


Yes, there was a fad for making mattresses that sort of fold into a weak, uncomfortable couch. That combo is called a futon here. Now they have frames that give them some supportive structure, but the earlier ones looked like this: https://thehousingforum.com/single-futon/


Ah so it's a kind of sofa / pullout bed, with a continuous folding mattress instead of the older "split" style


One Codex (YC S14) | San Francisco (Mission) | Software + Scientist Roles | Onsite + Remote | https://www.onecodex.com

One Codex is a platform for microbial genomics. We are a technical, experienced team working on meaningful problems that range from infectious disease diagnostics to outbreak epidemiology to improving our understanding of the microbiome. We work with top researchers, medical institutions, and biotechs, and have processed samples from all seven continents (and space!). Here's what we're doing to help out with COVID-19: https://www.onecodex.com/blog/2020/03/16/covid-19-sequencing...

We're currently looking for engineers across multiple positions, including both full stack and DevOps roles. Our stack includes Python, Rust, and Javascript/Typescript (React), and we write everything from D3 visualizations to low-level bioinformatics algorithms. We are also hiring for a computational biologist, an account manager, and a marketing manager.

Challenges include: (1) developing novel algorithms for analyzing complex microbial communities; (2) working with terabytes of genomic data; (3) building scientifically reproducible analyses suitable for both research and the clinic; and (4) supporting scientists and developers building on our platform with extensible APIs.

We are based in San Francisco and offer a competitive salary and meaningful above-market equity. Benefits include full medical, dental, and vision coverage, and a flexible vacation policy.

Please apply here: https://www.onecodex.com/careers/


One Codex (YC S14) | San Francisco (Mission) | Software + Scientist Roles | Onsite + Remote | https://www.onecodex.com

One Codex is a platform for microbial genomics. We are a technical, experienced team working on meaningful problems that range from infectious disease diagnostics to outbreak epidemiology to improving our understanding of the microbiome. We work with top researchers, medical institutions, and biotechs, and have processed samples from all seven continents (and space!). Here's what we're doing to help out with COVID-19: https://www.onecodex.com/blog/2020/03/16/covid-19-sequencing...

We're currently looking for engineers across multiple positions, including both full stack and DevOps roles. Our stack includes Python, Rust, and Javascript/Typescript (React), and we write everything from D3 visualizations to low-level bioinformatics algorithms. We are also hiring microbiologists/computational biologists.

Challenges include: (1) developing novel algorithms for analyzing complex microbial communities; (2) working with terabytes of genomic data; (3) building scientifically reproducible analyses suitable for both research and the clinic; and (4) supporting scientists and developers building on our platform with extensible APIs.

We are based in San Francisco and offer a competitive salary and meaningful above-market equity. Benefits include full medical, dental, and vision coverage, and a flexible vacation policy.

Please apply here: https://www.onecodex.com/careers/


Hello. Do you accept remote from Europe? I'm in Romania (UTC + 3).


One Codex (YC S14) | San Francisco (Mission) | Software + Scientist Roles | Onsite + Remote | https://www.onecodex.com One Codex is a platform for microbial genomics.

We are a technical, experienced team working on meaningful problems that range from infectious disease diagnostics to outbreak epidemiology to improving our understanding of the microbiome. We work with top researchers, medical institutions, and biotechs, and have processed samples from all seven continents (and space!). Here's what we're doing to help out with COVID-19: https://www.onecodex.com/blog/2020/03/16/covid-19-sequencing...

We're currently looking for engineers across multiple positions, including both those who are backend- and frontend-leaning. Our stack includes Python, Rust, and Javascript/Typescript (React), and we write everything from D3 visualizations to low-level bioinformatics algorithms. We are also hiring microbiologists/computational biologists.

Challenges include: (1) developing novel algorithms for analyzing complex microbial communities; (2) working with terabytes of genomic data; (3) building scientifically reproducible analyses suitable for both research and the clinic; and (4) supporting scientists and developers building on our platform with extensible APIs.

We are based in San Francisco and offer a competitive salary and meaningful above-market equity. Benefits include full medical, dental, and vision coverage, and a flexible vacation policy.

Please apply here: https://www.onecodex.com/careers/


One Codex (YC S14) | San Francisco (Mission) | Software + Scientist Roles | Onsite + Remote | https://www.onecodex.com

One Codex is a platform for microbial genomics. We are a technical, experienced team working on meaningful problems that range from infectious disease diagnostics to outbreak epidemiology to improving our understanding of the microbiome. We work with top researchers, medical institutions, and biotechs, and have processed samples from all seven continents (and space!). Here's what we're doing to help out with COVID-19: https://www.onecodex.com/blog/2020/03/16/covid-19-sequencing...

We're currently looking for engineers across multiple positions, including both those who are backend- and frontend-leaning. Our stack includes Python, Rust, and Javascript/Typescript (React), and we write everything from D3 visualizations to low-level bioinformatics algorithms. We are also hiring microbiologists/computational biologists.

Challenges include: (1) developing novel algorithms for analyzing complex microbial communities; (2) working with terabytes of genomic data; (3) building scientifically reproducible analyses suitable for both research and the clinic; and (4) supporting scientists and developers building on our platform with extensible APIs.

We are based in San Francisco and offer a competitive salary and meaningful above-market equity. Benefits include full medical, dental, and vision coverage, and a flexible vacation policy.

Please apply here: https://www.onecodex.com/careers/


Those systems process up to 384 or 1056 samples in ~8 hours. The proposed method should support a similar volume (even a bit higher) than the Roche 8800, but with a different large installed instrument base. So this should add a lot of capacity to that qPCR.


They accepted more tests than they had the ability to quickly process. They also appear to have accepted many tests that required use of a lower throughput assay before switching to higher throughput testing on Roche 8800s: https://www.theatlantic.com/health/archive/2020/03/next-covi...


Thanks, googling found this[1] statement by Quest that they have a backlog of 115,000 tests, down from 160,000 on March 25th. It would be interesting to know what percentage of the California backlog is contained within that.

[1] https://newsroom.questdiagnostics.com/COVIDTestingUpdates


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