Kids are stupid and follow what adults do. If I judge that I have the time to cross the street at red light without getting hit by the incoming car doesnt mean that the kid standing next to me is even seeing the car and crossing right after me.....
Showing kids good example is good. What you mean is showing them bounderies.
Getting shit drunk in front of kids and telling them how much fun it is but they cant do it is behaving like a child
trains can be superfast. For example a tgv from strassbourg to marseille is 5-6h. Same with car is for me 8h. Bus is even slower so I would wildy guess 12h. Plan is btw 1 1/2 hour.
yes but there are so many
cases where they took the worst of the worst and gave them high profile jobs with way way way to much power for high ranking nsdap members.
Rheinhard gehlen and everyone around him is a something that could have been prevented.
And so many high class nazis where in such good positions because they where experts on anticommunism. For the americans and brits it was "safer" to give positions to exnsdap officiers then people from the SPD(socialists)
Gehlen kicked even the only high ranking spd member in secret service out
for god sake they even hired klaus barbie. that guy had entertainment partys where the guests could
torture jews homosexualls etc... and he killed most of french opposition.
Got hired from the bnd and cia as expert on anticommunism
Germany didnt change much..
fuck we even voted a full member of the nsdap as chancelor. Kurt kiesinger. Yes we had two Nazi chancellors!!
honestly the only reason the denazification was shit was because most people at power at that time where kind of nazis.
edit:// btw the DDR had somehow solved the problem and didnt had as much nazis in high position.
Frenchman here and so true. I was taking the bus and it was stuck in traffic and I was like "hey can you let me out I life right in that street and shit aint moving" .... no fucking way. had to wait 10 minutes and then walk back to my place... driver was completly
ghostinh me after he said the magic german words " I am not allowed to do this".
In france they Busdrivers let me out between stops if I ask them before.
Germany is crazy rule
obsessed. they also have the crazy mentality that if you put it into rule problem is solved xD
It’s clear how much Apple now hates the MacOS as we have known it… I think the concept of a computer which can run code outside a sandbox and without tollbooths that extract rents for Apple is abhorrent to them.
I think the vague plan is to iOSify it more and more until there is no real difference, including the lockdown and mandatory App Store requirement.
in all respect sorry this is wrong. this is a broad misinformation. It can enhance but also supresse cancer dependig of soo much we dont know yet enough to know if fasting is beneficial or dangerous.
edit:// and the article has imho nothinh to do with autophagy. Its about beige fat cells eating stuff away from cancer not autophagy wich happened in the innercell. And if you go into caloric deficit you could burn away those
beige fat cells that "heal" the cancer.
The paper you posted is just a review on autophagy and cancer that doesn’t contradict anything I stated. It is a mistake to conflate autophagy, calorie restriction, and cold exposure as necessarily biologically identical, which your comment seems to imply.
I was only raising questions this research and discussion made me curious about, not making any concrete claims.
Although the idea of calorie restriction as a cancer treatment is something still actively debated and researched, I personally doubt it is very useful, or likely to be the main mechanism here in the connection between beige fat and cancer, but it is a possibility to at least be ruled out experimentally in the context of the comment I replied to, which is why I mentioned it anyways. One major concern with calorie restriction in humans but not rodents is that it shuts down your metabolism by limiting t3 thyroid hormone production whereas cold exposure ramps up metabolism by uncoupling mitochondria to produce heat. You are correct that the body can shut down processes and systems that might be important for fighting cancer, in response to calorie restriction.
I am a researcher that studies metabolism, and actually think the prominent focus on fasting and calorie restriction as a potential medical cure-all has been mostly a dead end, that people were mistakenly led down largely as a result of these fundamental differences between rodent and human metabolism.
you are right now I better understand what you meant.
That was the part that confused me.
"If it does negate the benefit than that would suggest that the entire benefit from the beige fat is from putting the body in a calorie deficit, and you would then expect the exact same effectiveness from calorie restriction"
As far as I understood the paper its beige fat that can eat away food from cancer and not white fat. And afaik calorie restriction doesnt augment beige fat.
My error was thinking you meant calorie restriction while having white fat but you meant with beige fat? And yes this makes sense.
And I thinked autophagy because this is the main "thing" happenkng while fasting which is not burning body fuel
The comment you quoted was me paraphrasing what I saw as the implied idea that I was reading into the comment I was replying to. It's not what I personally suspect is going on here at all, but I can't dismiss it out of hand.
Yes, autophagy does ramp up during fasting, but it's just one of a number of different physiological changes that occur during fasting.
yes thats true if you survive it. Have two friends with a salary over 300k a year. one worked 5 years and retired the other bought more luxury products to reflect his income and is now completly burned out after 3 years but forced to work because of his 300k a year lifestyle
no people are stupid. Smart meters are paid by the grid operator like everywhere else. Friends of mine got one and it was 25€ a year for it.
Yes germans are very stupid. we fight everything new because we think this country worked rly well in the 80s and thats where we want to be 1980
Digital and Smart thats for othet countries.
I got air air heatpumps for 3 rooms 1000€ a room and it slashed my heating cost to 1/3. And I have to explain that its not foor cooling but for heating and then the response is " heatpumps are like 20k plus you liar" or " heatpumps dont work in the cold" ... germans
Still many people dont switch because the read somewhere about magic costs that dont exist. Russian Gas propaganda is big here
smart meters are paid by the grid operator and you have to pay maximum 50€ a year for a smartmeter. I honestly dont know where you get your numbers. a friend with a big house and 3 children switched to air water heatpump with floor heating etc and it was 18k€ and half of that paif by the state and the smart meter was mostly free( he pais 25€ a year for it).
and this is a hugeeee house. No solar but he is working on it.
could you link some proof of this smartmeters I have to pay? Or some calculations from firms it whatever that proof your point.
Think about cabinet from 1972 for one electricity meter. Now you have one electricity meter for house electricity and second one with dynamic plan for heat pump and spare place prepared for third meter for wallbox. So the new cabinet costs you 3000€ including my work and it’s not seldom, that the house has no grounding rod. With couple small repairs/upgrades it’s 4000€ without VAT. And since everything must be documented I can’t work without invoice.
It has nothing to do with smart meters. Some electrical installations are heavily outdated by today’s norms. And norms are obviously written by greedy suppliers of the cabinets and parts for them. Worst thing is that I can’t make any money by selling this stuff. It’s already too expensive for the people. And it will not be cheaper with Paragraf §14a EnWG.
i installed mine myself and probably illegaly. But its super easy and those people who install it do a shit job sometimes. I watched professionell people flushing those pipes with compressed air....
And the fine is nonexistent so everyone should do it themself.
Showing kids good example is good. What you mean is showing them bounderies. Getting shit drunk in front of kids and telling them how much fun it is but they cant do it is behaving like a child
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