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Which school was this, and when did you attend?


The public school system near Columbus Air Force Base and I attended for 3rd and 4th grades (taking 7th and 8th grade English and science courses) in the '74 and '75 school years.


What did you do when you moved and your new school was expecting you to do 5th grade work?


For reading, worked through a box of SRA booklets in a couple of weeks time and then went to the library for the rest of the year --- mostly I was bored and coasted until my classes caught up, and even then, I was able to get decent grades w/ minimal effort.

Of course this all came to a head when I was a junior and the school system couldn't find a teacher for Calculus for myself and the couple of other students who wanted it which pretty much killed my college prospects, so aced the ASVAB, DLPT, and EDPT and enlisted.


Trisk Bio | Software Eng, Hardware Eng, generalists, ops | London, England | Full-time | ONSITE

We are looking for: hardware and software generalists; general generalists; mechanical, fluidic, and biochemical engineers; biologists; bioprocessing scientists.

We recently raised an $11M seed round, from top-tier investors and founders from the USA, mostly SF.

We are building in Stevenage, UK (https://twitter.com/gaurav_ven/status/1489891501459091458?s=...) - a short train commute from Central London (28 min), or East London (21 min), or Cambridge (37 min). Being on-site is important for what we do. We sponsor visas and hire globally.

We're building a new kind of fully-automated 'scale-out' manufacturing facility for biologics.

Our goal is to allow therapeutics companies to manufacture production-scale batches of product in many parallelized, benchtop-scale pieces of kit. This matters because 'scaling-up' from bench-top to production is crazy difficult and stochastic, and causes biological innovators to lose control over their products.

We are a very small team with expertise across biology, regulatory affairs, mechanical engineering, and physics. We intend to keep the team small through construction of our first manufacturing facility. We have a history of working together to accomplish difficult things, including getting mass Covid tests deployed across the UK (https://twitter.com/Dominic2306/status/1410734875708063746).

We hire people above roles. And we hire for values above specific skills. We value: courage; curiosity; motivation; resourcefulness; taste; commercial orientation; playfulness; technical excellence; the ability to both ideate and execute, and the judgement to know when to do which.

So reach out! We very much look forward to hearing from you.

Gaurav Venkataraman / CEO and cofounder / gaurav@triskbio.com


There is a very good book on the origins of life on earth by Eric Smith, called "The Origin and Nature of Life on Earth."

Here's a YouTube talk with some of the arguments: https://www.youtube.com/watch?v=0cwvj0XBKlE


Gallistel wrote a book 'Memory and the Computational Brain,' in which he argues that neural storage and computation via synaptic strengthening alone is implausible, and that the brain must have a real read/write memory. He points out that genetic material is an ideal substrate for such a capacity...


Indeed. There is even stronger recent evidence for the role of RNA in intracellular storage of behavioral memories: http://www.eneuro.org/content/5/3/ENEURO.0038-18.2018

Not to mention quite strong but now forgotten evidence from the 50s...

Can you email me at gauravvman at gmail? I have been working on demonstrating that neural computation is RNA based; would be interested in hearing your take on the field.


Indeed. Eva is a spectacular scientist, and one of the pioneers of this field.


I didn't downvote, but the reason is likely because your comment is off-topic. The parents are talking about experiences un-learning one-sided equality that they picked up programming before learning algebra; your comment is about programming a T-83 to help with schoolwork.


There was a recent interesting paper on the arXiv which argued that the ubiquity of small-world networks was vastly overstated.

Can't find the paper anymore - did anyone else see this / have a link?


I remember there was a paper regarding scale-free networks. I believe it was discussed on HN a few months back:

https://news.ycombinator.com/item?id=16144867

But I also (perhaps falsely) remember a discussion that seemed to challenge the small-world networks as well, so that may not be the discussion I was thinking of. I may not have engaged my brain at the time but I'd be surprised if it was small-world networks given the widely-reproduced evidence for the effect.


Yes! That is the paper I had in mind! Thanks.


I did some accidental market research on Snap with my girlfriend's 9 year-old cousin this weekend.

She had tons of snaps, but informed me that they were almost all blank images. She and her friends send each other these blank images to maintain 'streaks,' which count the number of continuous days that two people have messaged each other.

So attached to these streaks were the cousin and her friends that if the 24 hour mark was approaching and the cousin hadn't sent a blank message to her longest streak, the counterparty would log-in to the cousin's snapchat and send _herself_ a message, to make sure the streak continued.

My cousin said that the blowup in (blank) picture messages had slowed the app to a crawl, leading her not to use it anymore, aside of course for streaks.

Not the kind of of daily-active-users that advertisers crave. I'm 28; never heard of streaks before this.


One of my friends does this with his long-term girlfriend. I think they're at something like a 3 year streak at this point. They've exchanged username/password credentials to keep the streak alive in the event one of them forgets or my friend messes up his phone so badly he can't get it to boot. He's very enthusiastic about custom ROMs on Android so bricking his phone is not out of the ordinary.

edit: he says they've done that at least twice


"A metric that becomes a target ceases to be a good metric." ;)


Could you give some examples?


Like the other poster mentioned crypto currencies. I've hit many jackpots like this in my life. I have also seen big opportunities that are specific to another person, asked why they don't pursue X or Y, and the responses are quite often non-responses.

I literally begged several of my friends to just put $10 into a specific crypto that went up nearly 500 times. I did put about $100 myself into that one, and of course 20 similar parcels of money into about 20 others.

Of course just citing one example like crypto is not helpful. I had another idea for a totally passive income business, that I for whatever reason didn't feel like pursuing, I tried to convince others of the merits of doing this things. Eventually after about 2 years of failing to convince anyone else to try it, I did it, and made really lucrative money that came in like clockwork with about 2 hrs of effort per month. That thing ran for quite a while and eventually the market changed to not make it work anymore.

I have had some other successes too. I also lost of lot of thr easy money made along the way, but now I am wizer, and my latest money maker (post early crypto buying) I have taken a serious amount of thought about not ever letting it dissapate. I have also had many failures because I have tried many things. But some things really are no brainers.

Another example is buying massive bargains when shopping second hand. The trick to capitalise on a bargain is just 2 steps - step 1 make sure there is no catch (or a sufficient margin of safety) - step 2 - pull the trigger FAST - exceptional bargains don't hang around indefinitely.


> step 2 - pull the trigger FAST - exceptional bargains don't hang around indefinitely.

I find this interesting because I have a friend get bargains that saved him the equivalent to large percentages of his income on deals that were simply unbelievable. He is seemingly average tradesman...

I have been trying to train myself to get better at finding/creating and then jumping on great bargains, to understand his skill and the skills of others.

However there is a lot lot more depth to it than the two sentences you added to the bottom of your comment ;)


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