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Idk if you ever shared this view with art people. It must have been hard because there is a sort of obligatory necessity that people MUST like art embedded into their worldview. But also, there is a basic universality of art, and I wonder where it comes from, and what would make some people into it, and others, like you, not into it.


HAHAHAH don't even get me started on how bad anaconda is. On how slow the installer + interpreter, how they avoided being a part of the usual pip workflow, bloated environment, cross platform inconsistencies, extremely slow dependency resolution, etc etc etc...


Plus it took the name of an existing (fairly big) project


I'm not familiar with the medical side of this study, but I am very familiar with the statistics.

### They did not do a non-vaccinated vs vaccinated people comparison

These studies are observational, and in that sense no manipulation (such as random treatment assignment) was made. So they need to rely on observational studies techniques.

From what I could gather, one of this observational techniques in inverse treatment probability weighting when they say

> "we adjusted for all baseline covariates using stabilized inverse probability of treatment weights"

The IPW technique basically tries to solve the problem that some groups of children might have a higher prevalence of the treatment by weighting them in a manner as to mimic random assignment. This is as close as we can get to comparing treated and untreated in observational settings.

Also, the division of the doses of vaccine is also a better characterization of "was vaccinated". If you think getting vaccinated causes something, then getting more vaccinated should increase the incidence of that something.

### Wouldn’t you need a sizable cohort of non vaccinated children?

Yes, but as you pointed out, that might not exist. So by creating comparable groups (via IPW) + treatment intensity/dose we can still arrive at some conclusions.

### The researchers discarded from their cohort 34,547 children for receiving too many vaccinations/too much aluminum (...) Wouldn’t that data be relevant to look at?

They probably did. A few things are important here. The data comes from administrative data sources, so mistakes can happen. While you need to trust the sources, there could be imputation typos, or just weird cases. So the researchers probably went after a notion of "clinically relevant vaccine dosage for this study" to know up to which point to consider data points, because from that point onward, it either is not interesting because its a rare treatment incidence, or just seems like a mistake.

### “adjusted hazard ratio (95% CI) per 1mg increase in aluminum received……” and in the chart Asperger’s is listed at 1.13 (.89 - 1.44) so they do potentially see an increase for Asperger’s

Important to say that with hazard ratios, a HR of 1 means that there is no change because we are in the multiplicative scale (as opposed to 0 meaning "treatment does nothing" in the additive scale).

So in this setting, after adjusting for the treatment probabilities, a HR CI of (.89 - 1.44) just translates to 'no effect'. Nothing out of the ordinary in terms of the interpretation.



Nobel _Memorial_ Prize in Economic Sciences

That’s not a Nobel Prize.


If that’s the distinction, it would have been helpful for the original comment to note that they were just sharing some silly trivia instead of making a point.


It's not a silly piece of trivia, it's a completely different thing than what people think of as the "Nobel Prize", which is the set of prizes established by Nobel's will, not an unrelated prize named after him to leech off the prestige associated with his name.


The reason people correctly view this as silly trivia is that it's hardly an "unrelated prize." The Nobel Foundation administers the Economics prize in the same manner as all the others, and the awards are given at the same ceremony. You are making it sound like it's entirely separate when it's not. I don't think the Nobel Foundation was trying to "leech off the prestige associated with his name."

AFAICT your take exists entirely to delegitimize economics as a science. Very childish and frustrating.


>> It's not a silly piece of trivia, it's a completely different thing than what people think of as the "Nobel Prize", which is the set of prizes established by Nobel's will, not an unrelated prize named after him to leech off the prestige associated with his name.

> AFAICT your take exists entirely to delegitimize economics as a science. Very childish and frustrating.

You know, real sciences don't need shiny medallions to make them legitimate. I'd say your comment delegitimizes economics more than the GP's.


The price was created, and is given, by the Nobel Foundation, which was set up by Nobel's will to carry out his last wish. If you go to the official page of the Nobel Prize the Prize in Economic Sciences is listed with the other Nobel Prizes. Its not one of the original Nobel Prizes, but claiming its a completely different thing is not true.


The price was created by Sweden's central bank, not the Nobel foundation. It's true that it's now considered a Nobel prize proper for most, but that's not to say that it originally wasn't the economics field leeching on the scientific prestige of Nobel. To be honest, it feels pretty on-brand for it. And fwiw, in Swedish, it's almost always clearly distinguished with a "in memory of Nobel" or similar in the surrounding context.


No it was funded by Swedens central Bank. They provide to money for the prize to the Nobel foundation. Step it up if you want to be pedantic please.


1. It was set up during the Central bank's 300-year anniversary.

2. Without the central banks establishment of the perpetual funding there's no prize. Your argument is purely semantic and ofc snarky like your entire comment history.

3. You can read the story about it here in Swedish: https://sidea.se/nobelkuppen/ (The Nobel coup)


The way they presented the information, it is a silly bit of trivia. If there wanted to make some sort of argument about prestige or whatever, they could have made it. Dropping hints of some niche rabbit hole issue is not making a good-faith argument.


The comment means remember 1974. Cough cough Hayek... cough... Samuelson...


What are we afraid of summoning Voldemort or something here? Just say whatever you are coughing at, lol.


The so called "Nobel Prize in Economics" wasn’t created by Nobel himself, a scientist and engineer, but by a grant from the Swedish Central Bank. The actual money for prize every year is not paid from the Nobel foundation funds, is paid by the endowment created by the bank. It pays the Nobel Foundation administrative expenses and the monetary component.

Its basically economists trying to launder their way into science by proximity. Like Astrology lobbying to get a physics badge.

So as example in 1974, they awarded the prize to Friedrich Hayek and Gunnar Myrdal. Two economists whose views could not be more opposed. That is like awarding the Physics Nobel jointly to someone who says “objects fall down” and another who insists “objects fall up.” Or honoring two chemists, one who says “water freezes at 0°C” and the other who claims it freezes at 5°C.

And if you say that would never happen, because physics has actual empirical standards then yes, exactly. You get the point.

Even Paul Samuelson, a 1970 economy nobel laureate and actual champion of applying mathematical methods to economics, dismissed Hayek’s most famous work.

Which, intentionally or not, remains the most accurate definition of economics I’ve ever seen: A discipline where ideology often outweighs evidence and both sides get prizes.


he was a decade early


just use it on pc. It gets most of the benefits for contact maintenance. You can still watch the reels you are sent. But no reels, and the feed scroll gets very boring suddenly.


I feel I could use it more. I use the link jumping all the time, but that's basically it. What other features do you guys use?


Shift-T: triggers a tab switcher

D-U: is Page Up/Page Down

/: find in page


Genuinely curious, how you manage to derive value from this kind of LLM-assisted reading. At least in the areas I know, the gpt summaries are wrong and generic enough to the point that a read of the book summary, or a read of the preface, is more useful than what the AI returns. If I want to summarize something I provide, it works great. But for these more general overviews I don't trust it.


The handful of business style books I have run through it are wildly accurate and did a great job of summarizing the book chapter by chapter. I would probably not rely on it for technical books but for business books that often have only a handful of key ideas, it works great.


Ill mention a few books and how they've helped me become a better programmer.

- Structure and Interpretation of Computer Programs: this helped me understand the different types of recursion; how a problem can be modeled for the code to solve and how those designs can evolve and how the paradigm I'm using (functional or OOP) can help me

- Refactoring: this book helped me understand the different patterns we can use to alter code. Giving them a name and symptoms is a great way to apply and communicate with other coders. I recommend this book to everyone.

- The little Lisper: this really helped me get recursion. Like really. Although I could use a refresher.

- Clean code: look... this book is bad. Like, really bad. But, at the time I read it, and in the languages I used (Python, C, R) we didn't have many rules on how to write and organize our programs. And I wanted to improve on that skill. And this book gave me pointers and made me think about those ideas. I don't recommend it around, because for many people Clean Code can become a dogma really easily. But if you can question and critique and reach out to other resources and is an advanced beginner to coding, I can see this book bringing value.

- An Elegant Puzzle and Staff Engineer by Will Larson: those helped me get clarity on the role of the technical team in an organization. A team that produces code as the main driver of impact in a product/service. I lump them both because I read them back to back and don't remember, exactly, which is which. But une is more focus on a tech leader and the other a tech specialist.

- Unix and Linux System Administration Handbook: whenever I need to interact with some unix technology, this book delivers in terms of giving me a nice historical view and presenting the common tooling around the tool. This helps me interact with stuff programmatically much better. Be it GRUB, X, SAMBA, this book gave me the necessary introduction I needed, much more organized and thought out and with useful references than the average blog post you will find in the wild.

And I'd like to recommend this Ask HN on problem solving books

https://news.ycombinator.com/item?id=33797862


thanks a lot for your recommendations and how they helped you!


> I think math exists to solve real problems, so we should give examples of solving real problems.

This is a view that, depending on the lecturer, can be the total opposite of their view. See, many mathematicians don't have this instrumentalist view on math and some even despise it with their heart. They don't care about applications and don't get particularly excited when a problem was solved in another domain with their technique.

Also, solving a particular problem is that, a particularity. They look for generalizations and for rules and methods that can be applied regardless of the domain. That is why weird and contrived examples are the bulk of their logic, since when you look for generalizations, those are the cases where it breaks. Does continuity implies differentiability? For almost all practical cases yes, but when you want to be general, thats when you get the Weierstrass function [1], a weird function that needs to be studied if you want to develop a theory of real valued continuous functions. Yet, such knowledge is extremely impractical for you average engineer or deep learning researcher.

And ok, you might argue that "I'm not at such level, I don't need those particular theoretically interesting cases since I'm not going to study advanced mathematics at that level". Ok fine, I respect that. But that is not part of the "culture" of mathematics (a culture which your lecturer likely comes from). Since the subject is learned and investigated with this "quest for generality which makes us study weird examples" this is how it is passed along, and this is how it is studied and structured.

All that to conclude: I think its best to respect how math is structured. First, it is precisely the type of thought that I think very other applied fields lack, but that actually helps solving problems. It is by seeking generality, and looking at corner cases that stuff gets built. And mathematicians are the best at formalizing those because this is how they advance their craft. Second, and last, its by creating your own investigation and development of examples that you can stride for a more applied and practical version of the course. That way you'll get the most out of the course.

[1]: https://en.wikipedia.org/wiki/Weierstrass_function


> Does continuity implies differentiability? For almost all practical cases yes, but when you want to be general, thats when you get the Weierstrass function [1], a weird function

Ok I have to jump in and disagree with you. Non-differential continuous functions are far more ubiquitous (and useful) than you're suggesting here. The most obvious examples are the absolute value function and ReLU (rectified linear unit) activation function which turns up in a machine learning/neural network context.

I think you're thinking about being non-differentiable everywhere, but it's very easy to cook up examples of practically relevant functions which turn up to be non-differentiable somewhere.


symptoms can change through time, and be triggered by life events. It can be that a person had the coping mechanisms for one manifestation of symptoms, but due to external events, they don't work anymore.

The book I'm reading, Taking Charge of Adult ADHD, mentions that for an evaluation and diagnosis to be reliable in adulthood, the current form of symptoms should be happening for the past 6 months.

great book btw, highly recommend it.


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