Done occasionally it’s fine. It can lead to crashes and also anger or increased irritability. Things that mess with neurotransmitters can be hit or miss. A better long term strategy is to focus on fundamental things that improve the metabolic health of your cells.
One other “light” supplement that can dampen addictive behaviors or cravings is l-theanine.
In 1934, David Hilbert, by then a grand old man of German mathematics, was dining with Bernhard Rust, the Nazi minister of education. Rust asked, “How is mathematics at Göttingen, now that it is free from the Jewish influence?” Hilbert replied, “There is no mathematics in Göttingen anymore.”
The impact extends beyond mathematics. We have seen some pretty positive outcomes for LLMs as an assistant for scientists - with a lot of custom agent dev though - and not off-the-shelf models.
This is already being used by a few hundred scientists in a lab. We are aiming to extend to thousands next year with a focus on CS, climate & bio.
Thanks! Most of the current work is not yet out as press or blogs - we generally do that post code release/ publications/ arXiv submissions. Will share them as they are made public.
MIT, the Steel Factory, Cal, UDub and what, 37 authors pushed a preprint and no one heard about it?
@dang I can’t be the only one who has had it on this GPT-5 test flight shit. I don’t care how many clean Azure IPv4 blocks Altman has, throw this motherfucker out.
I have found OpenAI to be the most superior in complex prompts especially where written messages like “Get better, Mom” are expected in the images. The distant second would be ideogram.
I am using these tools to send custom personal messages to close friends and family.
I have only interacted briefly with Sam but I found him to be one of the smartest YC folks. But I will let a Paul Graham essay speak [1]:
Honestly, Sam is, along with Steve Jobs, the founder I refer to most when I'm advising startups. On questions of design, I ask "What would Steve do?" but on questions of strategy or ambition I ask "What would Sama do?"
What I learned from meeting Sama is that the doctrine of the elect applies to startups. It applies way less than most people think: startup investing does not consist of trying to pick winners the way you might in a horse race. But there are a few people with such force of will that they're going to get whatever they want.
