If you're wondering why the wolves weren't given the impossible food challenge at 5 months, the author notes in the comments:
> @K9TrainerTina: they were, actually. however, the 5 month old wolf pups mostly just went to sleep after initially failing to get the food, so they were excluded from the analysis.
Also, rabbit haemorrhagic disease, which was investigated as a possible agent, then "escaped" from the lab "accidentally". Both didn't really work long-term.
Noting that the experiments described in the article were performed on yeast, can anybody better versed in biology convey a better idea on how applicable to humans these results are?
As described in the article, we both have telomeres, but as far as I know the comparison ends there.
As a guy who's done some homebrewing, yeast can handle alcohol concentrations which if placed in a mammal bloodstream would result in instant death. Its a matter of about 1.5 orders of magnitude not a minor difference. That has certain implications for what their cellular insides can tolerate vs ours.
So something in the cellular structure of yeasts "shields their innards" a lot better than cells in our body. A moderate booze fest to the deep innards of a yeast cell might for a mammal cell be achieved by merely sniffing an open beer bottle. It would require further research.
Its a particularly bad combo, using yeasts and alcohols to extrapolate to humans. Like "randomly" selecting a halophile to extrapolate human salt tolerance, or "randomly" selecting a thermophile to extrapolate human temperature tolerance.
I see no similar obvious reason not to extrapolate caffeine/yeast combo to humans other than the usual multi-cellular vs unicellular issues.
Well, this article states that caffeine shortens telomeres, and shortened telomeres are a hallmark of aging. Lengthened telomeres are associated with cancers. This seems to imply that the research done in this article (on yeast) correlates with the research you linked.
Noting that the experiments described in the article were performed on yeast, can anybody better versed in biology convey a better idea on how applicable to humans these results are?
Yes, I'd like to know too.
Which, if any of these genes that regulate telomere length are also present in humans?
You should consider checking out the game "Space, Pirates, And Zombies" (aka SPAZ), which is a more recent iteration on the top-down space shooter. Plus, it's also made by a two-man team.
I played SPAZ a bit shortly after it came out. But then I found myself having to grind only a few hours in to make progress, and I just don't have time for that. Have I missed the point?
A more complete explanation of the glitch occurs earlier in the video, but he explains the basics of it after he performs the glitch (unfortunately dying in the process). Apparently three different exploiters found three exploits that, when combined, enabled this glitch. Quite fascinating.
"Each of the discovered vulnerabilities allowed any @yahoo.com email account to be compromised simply by sending a specially crafted link to a logged-in Yahoo user and making him/her clicking on it."[1]
"One moment of perfect Javascript."