Hah. According to Wikipedia: "The Datapoint 2200 used simple bit-serial logic with little-endian to facilitate carry propagation. When Intel developed the 8008 microprocessor for Datapoint, they used little-endian for compatibility. However, as Intel was unable to deliver the 8008 in time, Datapoint used a medium scale integration equivalent, but the little-endianness was retained in most Intel designs." Which I guess is a reason to use little-endian, though not one that's really relevant to anyone that's ever actually used an Intel CPU. (ARM, incidentally, was little-endian by default because the 6502 was.)