re-frame might be technically interesting, but you're switching to writing in a lisp, which is a very niche choice. That's not going to be an overall win for many people.
TIOBE is a terrible indicator generally. More activity doesn't mean more people are using a language. I wouldn't work for anyone using it to make decisions :)
The Cognitect website[1] lists quite a few success stories using Clojure. I would trust the names in that list far more than TIOBE.
But really what sold me on the language was the quality of the libraries, the incredibly helpful community and its shared focus on simplicity. Reading about a thing is no substitute for hands-on experience; its hard to judge the trade-offs you're making without it.
