> one that incorporates an independent, statistically rigorous confirmation of a researcher's central hypothesis. We call this large confirmatory study a preclinical trial. These would be more formal and rigorous than the typical preclinical testing conducted in academic labs, and would adopt many practices of a clinical trial.
As you can see above and from your quotation (and like many other folks who come in to save the day), this article is heavy on plans and short on who is going to do the work. Of course I support papers where every single experiment doesn't have to play p < 0.05 games, but other parts of the article wander in other directions. That's all I'm reacting to.
Having a higher threshold for publication can be imposed without detailing who does what work. You might argue that this means less research will get produced, but it's probably worth it. Practitioners underestimate the difficulty of transferring knowledge to outsiders because of frictions due to trust, clarity, and tacit knowledge.
When you call for everyone to scale their experiments up by sixfold, I think you also need to consider the logistics of doing that. I'm totally in favor of better, more rigorous experiments, but I know that we couldn't afford the time, space, or gear needed to do that right now.
As you can see above and from your quotation (and like many other folks who come in to save the day), this article is heavy on plans and short on who is going to do the work. Of course I support papers where every single experiment doesn't have to play p < 0.05 games, but other parts of the article wander in other directions. That's all I'm reacting to.