For several past projects I've struggled a bit to determine what should be the most important things to focus on. Should it be (new) visitors, conversion rate, app/website usage, retention, user satisfaction, all of those..
I'm guessing that on the one hand it would be best to keep tabs on everything, but at the same time that causes you the lose focus. At least I've notived that I'm most productive when I focus on one thing at a time.
An alternative would be to regularly switch between the different KPIs (Key Performance Indicators, I'm using the term loosely here).
So, what do you consider the most important KPIs for the first 100 users (and which tools do you use to track them)?
Also learn from your mistakes. If you had that one really bad client, look at why there were bad to you. Avoid those mistakes next time. Document it, tell your team whatever. If releasing a critical feature broke things in production, again learn from it. Why did that happen and what can you do to minimize the risk of that happening again ?
If a client leaves, ask them why they left and what could have been done to keep them with you ? Sometimes, the answer is just "I don't need this anymore" but a lot of times you will hear things like "You guys don't have this thing that I really need" or "I need better support", "too expensive for me" etc. Anecdote: I have been successful in retaining a few clients by offering reduced pricing but with reduced features as well because they didn't really need all that fluff.