How many of you or people you know would run away from new treatment trials ? I've been surprised to see a few people getting more than annoyed at suggesting it. "I'm not a guinea pig" was the recurrent answer.
If you have no options left, I suppose it's the only sensible thing to do. Either you're 100% sure you die from cancer, or you take an unknown chance that might save you.
Then again, not all people are very capable of rational thought.