I have been recently considering getting my genome sequenced. It seems like, if one of my main priorities in my life is longevity, this would be one of the most cost-effective ways to find out what factors are likely to influence that, and change my behavior based on the results. $1000 seems steep, but if you think about it over the course of a whole life, it's not so bad...thoughts?
I think my biggest thought would be, assuming you had your genome sequenced, what could you do with it? I can think of a lot of theoretical things, but I think every inspection of that genome for something would cost money (possibly/probably more than the cost of sequencing). I may be wrong about that, though.
You can quite easily do stuff like mutation calling and differential gene expression analysis with subsequent gene set enrichment analysis for free on a standard computer. You'd need to know what you're doing of course, but in terms of costs, it's definitely manageable. That's if they provide you the raw data, though, which doesn't seem to be the case with a lot of providers.
