As I mention in another reply -- I'm not saying this filtering would result in the most interesting feed, but it's frustrating you can't filter your feed at all.
If some people want more interesting opinions, great. If others want more bland but less abuse, also great. Right now you can't filter for anything and most of tweet replies are a giant waste of time.
The real problem is that reputation can't be absolute but is relative to a context. Hence the blockbot partial solution.