"...studies which point out some interesting large scale trends. One that private pharma R&D is getting less efficient, creating fewer and fewer drugs per billion dollars"

All the more reason for the State to involve itself here by bringing to an end such an expensive,'inefficient' (or more likely self-serving, profit-driven) system. As I've said above, it's the job of Government to protect its citizens from such abuse and in this matter it's high time it started.