I use the official HA docker version (not Hassio). It exactly replicates a manual installation of HA.

Works great, I use it in network host mode because I did it by mistake initially and suddenly discovered a few devices which joined via broadcast (my Logitech Hub especially).

I recently installed hassio in docker on a VM on a fitlet2 (also running asterisk and pi-hole on the same machine each in a separate VM). So far no problems controlling a TV and some z-wave light switches.

I run it virtualized. Have not come across any cons ( though I do not direct attach any devices, so don’t deal with configuring pass through yet )

Yeah, fundamentally it's just a Python application. I run it in a virtualenv on my Ubuntu desktop.