Good luck doing it on mobile phone. I'd say 99.99% users out there on mobile never even attempted to use another browser than safari or chrome for ios.
Well, once a webpage has played audio there's a notification that hangs around till you restart the phone. That's probably better than the cost of running Chrome, though.
I’m using safari + adguard (an app that injects adblock rules into it) and pretty sure that I see no ads. Except on few sites that usually try to push it even through desktop uBO anyway. Even no youtube ads, idk how they do it.