I have had a matrix instance on one of my servers running but integrating Jitsi was a real pain. And even when the integration is done correctly the user experience of using it within Matrix is at least weird. It appears as an "attachment" in the conversation and is very non-intuitive for everyone.
Jitsi is much easier to add in the latest Riot-web version. No longer do you need to set up your own integration manager. You just add the jitsi URL to Riot's config.json and you're done.