The funny thing is, back in the day I wrote a 8080 emulator that could run CP/M programs on MS-DOS, and then I went the extra mile and adapted it to run ISIS-II programs for the Intel blue boxes we had. There were some 8051 Dev tools I thought were worth bringing over. But that would have been in the 80s, and the 8 inch drives went to the landfill decades ago. So yeah.
Of course if you had a NEC V20/V30 (pin-compatible 8086 clone), it had a special mode for running 8080 code! It couldn't run Z80 code because it lacked the extensions like LDIR.