Running a different test the slowest part of the python script is the startup time, otherwise they're identical:

    [admin@localhost ~]$ time ./test.py
    real 0m0.295s
    user 0m0.158s
    sys 0m0.138s

    [admin@localhost ~]$ time ./test.pl
    real 0m0.164s
    user 0m0.158s
    sys 0m0.006s

    #!/usr/bin/env perl
    use 5.16.3;

    open my $fh, '<', 'logs1.txt';
    while (<$fh>) {
    chomp;
    if (/\b\w{15}\b/) {}
    }
    close $fh;

    #!/usr/bin/env python

    import re
    regex = re.compile(r'\b\w{15}\b')

    with open('logs1.txt', 'r') as fh:
     for line in fh:
      if regex.search(line):
       continue