My big complaint is that this means I get no value from my Tridactyl keybindings. I would use reader mode on almost everything by default if it weren't for this.
Sorry, I didn't pay enough attention when reading! That is actually pretty nice and one could use this to implement a reader-view browser extension. I like that it uses seccomp for the HTML handling as well.
You can block 99% of ads using just the hosts file as well. Also
reader mode blocks out everything other than static images and
text, and static images as ads are almost non-existant
nowadays(unfortunately).
You're right and it all depends on what you consider acceptable or not. Still, reader mode will let some things slip through, like cookies, which could be especially undesirable on blogging sites like Medium.