A year or so ago I spent probably 2 months to try and find a keyboard that had the layout I wanted.
Also when pressing Ctrl+F4 I use the outside of my hand to press Ctrl, then my index finger for F4. That means that the F4 key needs to be over or to the left of the #5 key, or else I can't reach.
I hate when ThinkPad lovers point out that it can be remapped in BIOS... it's not the same thing! The width of the keys is different and at least in my sporadic use of colleagues' ThinkPads, it's been a major pain point.
Also every laptop has a different - stupid - keyboard layout.