I think the big reason the ASCII C0 characters never took off was because you can’t see or type them.[a] If I’m writing a spreadsheet by hand (like CSV/TSV), I have dedicated keys for the separators (comma and tab keys). I don’t have those for the C0 ones. I don’t even think there’s Alt-### codes for them.

[a]: Regarding “seeing” them, Notepad++ has a nifty feature where it’ll show the control characters’ names in a black box[0]

[0]: https://superuser.com/questions/942074/what-does-stx-soh-and...