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A bit off-topic, but any idea how much it costs to get an experimental treatment like this?


The NYT article I linked to actually has two pages. The second page goes into more details on cost. Here's a direct link to both pages of the article: https://archive.md/Fwyo0

Here's the relevant quote:

> The Pennsylvania researchers said they were surprised to find any big drug company interested in their work, because a new batch of T-cells must be created for each patient — a far cry from the familiar commercial strategy of developing products like Viagra or cholesterol medicines, in which millions of people take the same drug.

> But Mr. Hoppenot said Novartis was taking a different path with cancer drugs, looking for treatments that would have a big, unmistakable impact on a small number of patients. Such home-run drugs can be approved more quickly and efficiently, he said, with smaller studies than are needed for drugs with less obvious benefits.

> “The economic model is totally acceptable,” Mr. Hoppenot said.

> But such drugs tend to be extremely expensive. A prime example is the Novartis drug Gleevec, which won rapid approval in 2001 for use against certain types of leukemia and gastrointestinal tumors. It can cost more than $5,000 a month, depending on the dosage.

> Dr. June said that producing engineered T-cells costs about $20,000 per patient — far less than the cost of a bone-marrow transplant. Scaling up the procedure should make it even less expensive, he said, but he added, “Our costs do not include any profit margin, facility depreciation costs or other clinical care costs, and other research costs.”


Wow, thanks! $20k is lower than I expected! I guess when they add in the other costs it will be a fair bit higher, but still.


Might still be reasonably priced if/when it's available in countries other than the US?

Specifically, countries that don't have a broken extremely-overinflated-pricing model for health care.


CAR-T (programmed t-cells for blood cancer) are around $400-500k not including the cost of harvesting and implanting them back into the patient.


Yeah $20,000 seems very cheap for such a treatment.

Also there are biohackers who synthesize their own insulin and even COVID-19 vaccines and test it on themselves. Their work may cause them more harm than good, but it's their bodies and they're free to experiment on it however they choose. When somebody has a terminal illness and is facing imminent death the risk calculus is very different where even taking the bargain basement biohacker version of a medication may make sense. (Though obviously this particular treatment is a bit different because it uses a modified HIV virus)


Software Define Drug? Similar to Software Define Radio.

Not sure if it good or bad...




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