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I did extensive research before I spent 8 months traveling around South America in the midst of the Zika outbreak and of course also concerned with Malaria. My conclusion after all my research was that anti-malarial drugs were less effective per dollar/effort cost than insect bite prevention. I ended up writing an article on the topic on my blog at the time: https://tristor.ro/blog/2016/05/01/trip-preparation-update-i...

I ended up treating most of my clothing and equipment with permethrin, using Picardin spray on my skin, hanging permethrin treated mosquito nets over windows and doorways, and as a final line of defense and for comfort I bought a cheap fan in each country I visited and left it behind in the apartment for the next occupant when I left, having it blowing on me directly at night.

Anti-malarial drugs all seem to have severe neurological or psychological side effects, and some can cause permanent damage, so just on the off-chance that anyone sees this that's considering traveling to a malaria-risk region, be aware there are other options.




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