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There is a new field of extracting wiring diagrams from brains at the level of individual neurons. This is what I work on.

http://openconnectomeproject.org has some introductory material. (This is not my site, it is by some people at JHU who picked up our data set and are working on it.) Massive image data sets, lots of need to develop workflow. You can browse the image data here: http://openconnectomeproject.org/catmaid/?pid=4&zp=40635...

Concretely, look at the plugins being developed by the Fiji project and pitch in, especially on the electron-microscopy-centric plugins: http://pacific.mpi-cbg.de/wiki/index.php/Category:Plugins

edit: also think about contributing to the CATMAID project, which is the software serving the browsable data set above, and perhaps will someday enable crowd-sourced markup: http://fly.mpi-cbg.de/~saalfeld/catmaid/



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