You definitely can drive actions from a spreadsheet — it's one of the most common usage patterns.

Here's a demo showing it in action: https://docs.browserflow.app/tutorials/tutorial-scrape-a-lis...

(The demo shows scraping each URL but you can perform arbitrary actions for each row of the sheet.)

As for Firefox, it's unfortunately not currently possible: https://news.ycombinator.com/item?id=29256938