This whole thread is off-topic (talking about AEAD in a post about signing), but:

You can use age's AEAD encryption with Yubikeys. Yubikeys can do ECDHE in PIV mode.

I wrote https://github.com/tv42/yubage as a subprocess plugin to https://github.com/str4d/rage (and hopefully https://github.com/FiloSottile/age once they think plugins are stable in enough to go in the reference implementation). The rage author also wrote their https://github.com/str4d/age-plugin-yubikey