Not saying I ever buy illegal drugs, but my venmo history is full of people buying $80 of pizza or $150 of sushi -- this seems to be seller's preference, as far as I can tell. No one in my rather wide extended circle has ever tried to or even suggested using crypto for these kinds of transactions.
That's because marijuana still counts as a drug. In young professional circles for non-marijuana drugs, there is definitely a major crypto backend even if you only deal with the middleman.
Going from cash to crypto is pretty expensive I think. I tried to do a large transaction thought crypto might work but it was going to be a couple hundred just to convert it
It's really not. Coinbase pro charges ~0.5% on cash to crypto trades. Strike charges a very small spread on cash to bitcoin, and you can send directly to other lightning nodes for < $0.01.
USDC can be converted from / to USD for free on Coinbase.