There are mechanisms that could cause that (“original antigenic sin”) and it does happen with dengue fever. Of course, it’s not true here, but it was reasonable to think it might be in 2020.
And covid vaccines being spike-only may be less effective against variants than whole-virus vaccines or actual infections. But flu shots manage to be ineffective a year later with whole viruses in them, so maybe that wouldn’t help.
And covid vaccines being spike-only may be less effective against variants than whole-virus vaccines or actual infections. But flu shots manage to be ineffective a year later with whole viruses in them, so maybe that wouldn’t help.