Yes - it’s bizarre to think the Roman Empire almost made it to the Columbus voyages. Columbus would land in the Americas just 39 years after Constantinople fell to the Ottoman Turks… who would themselves make it all the way into the 1900’s and fight in World War I!
1492 was the year 7000 in the Byzantine calendar (started with the creation of the world). There was a religious “year 7000” happening in the Eastern world (Moscow, etc) just a Columbus was launching his ships.