The reproducabilty crisis in chemistry is just as bad, if not worse, than biology. Anyone with a pen can reproduce a math proof. If you work on a big project (physics experiment) where every paper has a dozen eyes on it you can't slip crap work by your peers because that's their livelihood on the line. In between you have bio/chem fields where each project is too expensive to trivially reproduce but still small enough to have only one career on the line for each project.
Most of the reproducibility issues in chemistry happen in biochem in my experience(meanwhile it gets the most funding). That said, synthetic chemistry is also a problem area. Usually in synthetic chemistry it's not that the work can't be entirely reproduced, but rather that yields are fudged. That's mostly because PIs say "you can't graduate until this reaction yields 99%.". So after someone has written four papers, taught classes at minimum wage for 7 years, they fudge a 95% to a 99%. It's not okay, but neither is the way academia is structured. Super glad my discipline was elsewhere, but I saw colleagues suffer from this stuff...
