"Yes", is the short answer. Every ECMO machine I've ever seen uses a [1] peristaltic pump and, despite the use of tubes coated with anticoagulants and with various proprietary bits of chemistry [2] to reduce the size of the inviscid layer and hence shear stresses, the maximum length of time you can spend on them is limited. It's always a downhill battle and typically a "metric shitton" of heparin is infused in order to reduce the risk of thrombus, despite the hemorrhagic risk [3].
All of these things are fine balancing acts but you do not want to be on ECMO for a long time. Similar technologies, such as cardiac LVADs are only licensed in the UK as a bridge to transplant, for example, where a well-defined end-date already exists before putting the patient on them.
