You’re incorrect about the middle of tectonic plates being safe from earthquakes by definition. Locating naively built skyscrapers in New Madrid, MO, for example, would be a bad idea. [1]
On a geological timescale, tectonic plates occasionally rift down the middle, both successfully (East Africa) and unsuccessfully (a failed plate rift produced the Great Lakes).
With that said, identifying strata that are going to remain seismically stable for a looooong time is a solved problem, and earthquakes generally damage only those things not attached to the (moving) earth.
On a geological timescale, tectonic plates occasionally rift down the middle, both successfully (East Africa) and unsuccessfully (a failed plate rift produced the Great Lakes).
With that said, identifying strata that are going to remain seismically stable for a looooong time is a solved problem, and earthquakes generally damage only those things not attached to the (moving) earth.
[1] https://en.wikipedia.org/wiki/Intraplate_earthquake