My stationary PC is a modern AMD Zen 3 setup. It runs Windows 11 pro for workstations latest developer release, TPM and other settings completely enabled, no stuttering whatsoever.

That's great. Eventually I'll have to emigrate from Windows 10 as well. Hopefully AGESA 1.2.0.7 solves the problem.

I have a Windows 10, 5900X+X570 machine with fTPM enabled and I get zero stuttering. Still using a pre-release BIOS with early Zen 3 support from August 2020 since I never saw any need to update it.