Yeah. Lying down your glute is not activated as much. The upright position also gives better activation of the upper body which gives much better breathing.
Well if you go really really fast aero is the most important. The aerodynamics of an upright rider is worse than a semi truck. Also the breathing aspect is only really relevant for longer efforts. If you want to race 150 other guys through small European roads for 21 days in a row, up right is better.
Recumbent vs. upright is actually an over 100 year old battle, over misunderstanding each others needs and wants from a bike. Many recumbent people are still sour over UCI banning non-double diamond frames.
That said recumbents might be the most aero dynamic bikes, but lying down pedalling is less biomechanically efficient.