Now that 5.25", 3.5", and 2.5" drives are less common in PCs, it might be time to think of a new standard which puts the GPU in a new form factor which allows for better (or at least simpler) airflow through the case. Seems needless to blow hot air into and out of the GPU just because of where it is situated inside. Imagine only a small number of fans pushing air in a single direction in order to efficiently cool all the components in the system.