I think it has a special place in the hearts of people who are especially affected by interruptions, more because of what is concretely inflicted on the title character than because of the abstract argument about equality and inequality. There was no language for talking about being sensitive to interruptions back then, and there isn't really now unless you have some kind of diagnosis. My wife does not understand that speaking to me every ten or fifteen minutes affects my ability to concentrate and do my job. As an adult with a high-paying job, I'm able to rent space at a coworker space so that we don't have constant fights about it that affect our marriage. For children living in loud homes where people constantly yell and blare the TV, and trapped in classrooms with other children who scream and disrupt simply because they can't stand quiet, they have no ability to escape, but at least they have some validation in the form of this story, proof that a famous and successful person recognized their experience as real.
I always thought that the interruption theme was not at all the point of the story, but simply the most disturbing handicap from the perspective of an author.