Fun fact: The Macintosh II (68020) had two 6502 processors on its motherboard, somewhere in the I/O system. Originally intended to do some kind of I/O acceleration, they were never used by MacOS. I heard they just ran Mandlebrot-generation test code.
The IIfx, Quadra 900 & Quadra 950 each have two 6502 processors. They offload ADB processing (keyboard and mouse), the floppy disk and serial ports. MacOS uses all of them, NetBSD can use ADB offload.