The midlife crisis is a need for novelty, specifically the brain is not stupid, it sees that everything around is either collapsing or freezing in place and it wants to fight that, reverting to the days of college when everything was about building up and dynamism.
If and only if you get back to the same levels of building up and dynamism of the college days , and you are still sad/depressed, you could claim that the thing is not outward related.
If and only if you get back to the same levels of building up and dynamism of the college days , and you are still sad/depressed, you could claim that the thing is not outward related.