You will likely be able to find scientific studies toward any conclusion you want to make but there is objective evidence of this and in my own personal life significant anecdotal evidence. Given the OP title and topic and the massive reproducibility problem in medicine and perverse incentive problem in medicine, you will not be able to know the truth about the safety of medications to a high degree.
It is like the reviews problem on Amazon. All medications come with studies giving 5 star reviews. But the reality is nowhere near the same. Blackbox warnings and such are all we have to place a significant ding on this problem before taking the drugs off the market for clearly causing intolerable issues in large swaths of people.
This is a complex muddled issue. Argumentation with citations of 'articles' from journals likely will not lead to truthful discovery, unfortunately.
