I love Inkscape but for as long as I can remember it's always been laggy on a Mac. IIRC at one point there was a disclaimer on the website that the Mac version wasn't well maintained.

I'm running Inkscape 1.1 on an M1 Pro. I just measured time between clicking a plain rectangle and it being selected. It takes about 460 ms.

New 1.3 version takes 216 ms, about twice the speed. It looks a lot more usable!