I'm sure you can find differences, but here's an example adapted from the docs[1]:

  Gambit v4.9.5
  
  > (let ((x 10) (y (- 1 1))) (\* (/ x y) 2))
  \*\* ERROR IN (stdin)@1.30 -- Divide by zero
  (/ 10 0)
  1> ,e
  x = 10
  y = 0
  1> (set! y 2)
  1> ,(c y)
  4
  >

[1]: https://gambitscheme.org/latest/manual/#Debugging