No, because I don't want my termostat to switch off, my clocks to reset, my home server to go down every time I go to the shops or have a meeting. And no, I'm not about to rewire the house to provide isolated circuits just for the things I don't want to switch off, when I could instead just replace a few light switches and plug in a few smart plugs.

I can assure you pretty much nobody goes to their fuse board and trips the main switch even when going on holiday, much less during their day to day life. Many of the people who don't do that still tend to turn off as much as possible when leaving the house.