The Delancey Street Foundation focuses on adjacent / overlapping problems - recovery from substance abuse, convicted criminals re-entering society, and the homeless situations that often come with those situations. They have been remarkably successful and financially self-sustaining. I lived next to their development in San Francisco for 5 years and regularly patronized their retail businesses. For the first year or so, I had no idea about the foundation behind the businesses (or that their members were the employees) until I read something posted on the wall at one of them.

http://delanceystreetfoundation.org/

https://en.wikipedia.org/wiki/Delancey_Street_Foundation