Coffee and tobacco consumption is a known correlation (one of many refs https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158991/). Curious to see if authors considered that, as tobacco is one of the main aggressors of vascular tissue, which causes dementia in the long run.
EDIT 1: Just in time, UK Biobank (almost 500.000 people) study pointing to increased longevity with coffee consumers, an interesting controversy that just doesn't fit with their smaller study conclusion (although overall longevity is a different outcome, you would expect to find more dementia in older people) https://www.hsph.harvard.edu/news/hsph-in-the-news/coffee-lo...
Is it to tobacco because of nicotine? Or would things like nicotine gum and lozenges not count. I thought I recalled nicotine potentially being neuroprotective wrt dementia.
EDIT 1: Just in time, UK Biobank (almost 500.000 people) study pointing to increased longevity with coffee consumers, an interesting controversy that just doesn't fit with their smaller study conclusion (although overall longevity is a different outcome, you would expect to find more dementia in older people) https://www.hsph.harvard.edu/news/hsph-in-the-news/coffee-lo...