Not really, the only way it makes sense for a high level language to be used in a constrained competition is if the rules are specifically set up so that the runtime doesn't count towards the size limit. There are such competitions for Javascript, where you get 64kb of HTML to play with and the size of the browser itself is "free", or for Lua via the PICO-8 runtime, but I don't think anyone has done it for Python.
Write a Linux demo. You're allowed to use all the tools that come with the distribution (check the rules for the competition you want to enter, to see which distribution). I remember one with a Python shebang that launched SimpleHTTPServer to deliver a brotli-compressed payload to a browser.
