That’s so silly, these drugs aren’t even anywhere near the same league of effectiveness. There’s plenty of fat people who take nicotine all day.

Hmmm...if as many people consumed semeglutide you would have examples of fat people in that population as well.

You certainly would, because not every case of obesity results from the same mechanisms. But just as with all the other what-about comments, this comment misses the point: this class of drug is wildly successful, and it's the most specific drug for this problem that's been developed so far

https://www.healthline.com/health-news/ozempic-glp-1-drugs-m...

Here's a good piece running through the failure modes in lay terms.

This is genuinely one of the stupidest conversations I’ve been involved in. If nicotine was as effective as Ozempic at appetite suppression then everyone would know about it, it would be commonly used in medicine to treat obesity and Ozempic would never have been created. I hope for your sake this is pedantry instead of ignorance.

Sure, it's just not as good as Ozempic at doing that particular job.